Antibodies are an important part of the immune system. When the body is infected with an antigen, the immune system generates an antibody specific to that antigen. Antibody purification involves selective separation of antibodies from other plasma components (polyclonal antibodies), or from ascitic fluid or cell culture supernatant after large scale production using hybridomas (monoclonal antibodies). Immunoglobulins can be purified using affinity chromatography or affinity binding to immobilized protein A or protein G particles. During the projected period, the worldwide antibody purification services market is expected to rise at a significant rate.
The increasing focus of biopharmaceutical and biotechnology businesses on the manufacture of antibody-based therapies is one of the primary factors driving the growth of the antibody purification service market. During the COVID-19 pandemic, there has been a noticeable increase in demand for standard quality antibodies for research, diagnosis, and treatment, which has created attractive prospects for contract service providers with antibody purification capabilities. Many diagnostic technologies rely on the detection of antigens by antibodies. The monoclonal antibodies (mAbs) are commonly used in biochemistry, molecular and cellular biology, and medical research, their most important application is as therapeutic drugs for the treatment of human diseases like cancer, asthma, arthritis, psoriasis, Crohn's disease, transplant rejection, migraine headaches, and infectious diseases.
The exclusive COVID 19 impact analysis report by Axiom MRC provides a 360 degree analysis of micro and macro-economic factors on the antibody purification market. In addition, complete analysis of changes on the antibody purification market expenditure, economic and international policies on supply and demand side. The report also studies the impact of pandemic on global economies, international trade, business investments, GDP and marketing strategies of key players present in the market.
Due to the impact of Covid-19 disease there is a temporary lag in the antibody purification service market, but in the long run the antibody purification market is expected to grow and flourish at a significant rate in the forecasted period. The production of monoclonal antibodies was discontinued due to the COVID19 pandemic and had a severe impact on the world market for monoclonal antibodies, as they are widely used in cancer and gene therapy, thus influencing the world market for monoclonal antibodies. Although due to the emergence of Covid-19 various companies were working new therapy based on monoclonal antibodies for the treatment of COVID-19. The research was successful and got approval for emergency use by the United States Food and Drug Administration. Since due to this research and the potential of antibody purification service to cure or inhibit the growth of the disease rapid growth of the global antibodies purification service market is expected in the forecasted period.
The antibody purification services market comprises of different market segment like purification type, application, end user, and geography.
Antibody purification services market is based on the types of purification which is divided into three categories including physiochemical fractionation, class-specific affinity and antigen-specific affinity. In which antigen-specific affinity is expected to lead the market. The rising demand for antigen-specific affinity in different application is likely to boost the demand for market during the estimated time period. As antigen-specific affinity significantly helps in affinity purification in the sample that binds to particular antigen molecule through their specific antigen binding domain. Besides, physiochemical fractionation followed by class-specific affinity are likely to witness growing demand in market in upcoming years.
Antibody purification services market has number of application in monoclonal antibodies and polyclonal antibodies. On the basis of type of application, the monoclonal antibody is expected to be the dominating segment in antibody purification service market, due to increasing investment in monoclonal antibody research and growing new product innovation. Monoclonal antibodies have large applications in the field of diagnostics, therapeutics, and targeted drug delivery systems, which ultimately creates emerging new growth opportunity for the segment in antibody purification services market. Besides, the polyclonal antibodies segment is expected to witness significant growth in the forecast period because of easy production process, availability at a low price. The surge in demand for antibodies across research, diagnostic and therapeutic applications for purified antibodies is expected to grow to over the forecasted period.
The antibody purification services market finds its major end user in the biotechnology and pharmaceutical companies contributes largest revenue share in the antibody purification service market. Due to the large application of antibody purification service in biotechnology and pharmaceuticals sector there is increase in the production of antibodies purification service market. There is rise in the use of antibody purification service for the diagnosis of various diseases and the growing prevalence of cancer and chronic diseases such as diabetes. The second highest revenue generating segment in the antibody purification service market is research laboratories due to the increasing investment in antibody based research and drug discovery in various countries.
The global antibody purification services market is studied for the following region such as North America, Europe, Asia-Pacific and Rest of the world (RoW). North America is leading the antibody purification services market and will also lead in the forecasted period. Currently, North America is estimated to contribute to nearly 50% of the overall purification demand for clinical and commercial- grade therapeutic antibodies. Europe is assigned significant growth prospects in the forecast years due to increasing investments in health infrastructure. However, Asia Pacific is expected experience highest market growth during the forecast periods as a result of untapped opportunities in this region. The strong research activities in pharmaceutical and biotechnology companies are the key factor accelerating the demand for the market.
The key players in antibody purification services market are Thermo Fisher, Detai Bio-Tech Co, Cusabio, Genscript, Kmd Bioscience, Southernbiotech, Pacific Immunology, Covalab, Envigo and Ge Healthcare.
July 2020: Union Chimique Belge (UCB) did a license agreement with Roche and Genentech for the manufacturing and commercial production of UCB0107, which is a potent monoclonal antibody for the treatment of progressive supranuclear palsy (PSP) and Alzheimer's disease, but it is still under investigation.
June 2017: GenScript launched its custom rabbit monoclonal antibody service. With this, the company expanded its product portfolio.
March 2017: Thermo Fisher Scientific Inc. and Cell & Gene Therapy Catapult collaborated to optimize the advanced therapy supply chain.
The report analyses the antibody purification services market based on by purification type, application, end user, and geography. The antibody purification services is available in the market according to different purification type including physiochemical fractionation, class specific affinity, antigen specific affinity which further is divided in two applications monoclonal antibodies, polyclonal antibodies. The monoclonal antibody is the dominating segment so far in the antibody purification service market and is leading the market during 2021. The monoclonal antibody finds its major end users in biotechnology and pharmaceuticals sector there is increase in the production of antibodies purification service market Research company end user is anticipated to gain major market share during the forecasted period. The global antibody purification service market is studied for the following region North America, Europe, Asia-Pacific and Rest of the world (RoW).
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